Our Week 7 NFL injury report breaks down the biggest injuries for every matchup, including key starters, players on injured reserve (IR), practice participation, potential absences and injury clusters that could create advantages on the field. We highlight the most important injury news, how each team's overall health could affect performance and which matchups present the biggest injury-related betting angles heading into Week 7.

1. Patriots vs. Bears — Patriots OL and CB Crisis

Patriots

  • OL: Mike Onwenu (ankle, IR); Greg Van Roten (thigh, IR); Alijah Vera-Tucker (hamstring, DNP, OUT); Ben Brown (knee, DNP, OUT); Morgan Moses (foot, LP, questionable).

  • CB: Carlton Davis III (neck, LP, OUT); Karon Prunty (hamstring, LP, OUT); Channing Canada (hamstring, LP, OUT).

  • WR: Romeo Doubs (shoulder, IR); Mack Hollins (calf, IR).

  • LB: Harold Landry III (PUP).

Bears

  • RB: Kyle Monangai (thumb/toe, DNP, OUT).

  • LB: Jack Sanborn (concussion, DNP, OUT); T.J. Edwards (hamstring, LP, doubtful).

  • EDGE: Dayo Odeyingbo (quadriceps, IR).

  • OL: Braxton Jones (knee, IR); Jonah Jackson (hip/quadriceps, FP).

  • DB: Coby Bryant (knee, IR); Tyrique Stevenson (hip, FP, questionable).

Clusters: Patriots OL/CB/WR; Bears LB/EDGE.

Impact: New England's interior protection is severely compromised, with four guards unavailable and Moses questionable. The three missing corners create another major vulnerability. Chicago's linebacker and edge injuries partially offset the mismatch.

2. Steelers vs. Saints — Pittsburgh WR/Defense, Saints OL/DL

Steelers

  • WR: Roman Wilson (finger, IR); Ben Skowronek (calf, DNP)

  • WR Micheal Pittman (foot, IR)

  • S: DeShon Elliott (knee, IR, return window).

  • DL: Derrick Harmon (foot, IR); Sebastian Joseph-Day (triceps, DNP).

  • CB: Brandin Echols (hamstring, DNP); Jalen Ramsey (wrist, DNP).

  • EDGE: Alex Highsmith (groin, LP).

Saints

  • OL: Kelvin Banks Jr. (ankle, IR); Dillon Radunz (ACL, IR); Cesar Ruiz (knee, DNP).

  • DL: Bryan Bresee (ACL, IR); Nathan Shepherd (illness, FP).

  • LB: Kaden Elliss (calf, LP); Anfernee Jennings (knee, LP).

  • WR: Jordyn Tyson (hamstring, IR).

  • RB: Alvin Kamara (back, LP).

  • CB: Kool-Aid McKinstry (head/migraine, FP).

Clusters: Saints OL/DL; Steelers secondary/WR.

Impact: New Orleans has two significant offensive linemen on IR and Ruiz missing practice, while Bresee's ACL injury weakens its defensive interior. Pittsburgh has multiple defensive injuries, particularly in the secondary.

3. Bengals vs. Ravens — Baltimore QB/OL, Cincinnati Health Advantage

Bengals

  • S: Kyle Dugger (quadriceps, LP).

  • WR: Andrei Iosivas (thumb, IR).

  • TE: Tanner Hudson (pectoral, IR).

Ravens

  • QB: Lamar Jackson (ankle, LP).

  • OL: Ronnie Stanley (toe/ankle, LP); John Simpson (groin, LP); Andrew Vorhees (foot, LP); Cam Jurgens (concussion, FP); Ethan Pocic (knee, IR); Danny Pinter (knee, IR); Jovaughn Gwyn (ankle, IR).

  • WR: Rashod Bateman (shoulder, LP).

  • EDGE: Tavius Robinson (pectoral, DNP).

  • DL: Broderick Washington (ankle, LP).

Clusters: Ravens QB/OL, defensive front.

Impact: Jackson's ankle remains the headline, but Baltimore's offensive-line health is equally important. Three centers are already on IR but Jurgens available helps, and multiple starting linemen remain limited. Cincinnati is comparatively healthy.

4. Cardinals vs. Broncos — Arizona OL/RB/Secondary Crisis

Cardinals

  • OL: Paris Johnson Jr. (biceps, IR); Chase Bisontis (MCL, IR); Isaiah Adams (ankle, IR); Jedrick Wills Jr. (illness, DNP).

  • RB: James Conner (foot, IR); Trey Benson (knee, IR); Jeremiyah Love (ankle, DNP).

  • DB: Will Johnson (neck, IR); Budda Baker (groin/illness, DNP); Garrett Williams (knee, DNP); Andrew Wingard (knee, DNP); Max Melton (knee, LP); Wydett Williams Jr. (concussion, LP).

  • DL: Walter Nolen III (ankle, DNP).

  • QB: Carson Beck (back, LP).

Broncos

  • CB: Patrick Surtain II (ankle, LP); Riley Moss (ribs, FP).

  • S: Talanoa Hufanga (ankle, DNP).

  • EDGE: Jonah Elliss (ankle, DNP).

  • WR: Jaylen Waddle (chest, LP); Pat Bryant (ankle, IR).

  • RB: Tyler Badie (thumb, DNP); Jonah Coleman (ankle, IR return window).

Clusters: Cardinals OL/RB/secondary; Broncos secondary.

Impact: Arizona has one of the league's worst cumulative injury situations. Multiple linemen and running backs are already on IR, while five defensive backs were limited or absent Wednesday. Denver's secondary is improving with Surtain back at practice.

5. Rams vs. Raiders — Rams Lose Three Major Starters to IR

Rams

  • WR: Davante Adams (hamstring, IR).

  • DL: Poona Ford (triceps, IR); Kobie Turner (groin, IR); Myles Garrett (knee, IR).

  • CB: Trent McDuffie (groin, DNP).

  • LB: Nate Landman (concussion, DNP).

  • TE: Terrance Ferguson (ankle, IR).

Raiders

  • TE: Brock Bowers (hamstring/calf, LP).

  • DL: Tonka Hemingway (concussion, DNP); Folorunso Fatukasi (shoulder, LP).

  • OL: Kolton Miller (shoulder, LP).

  • LB: Quay Walker (chest, LP).

Clusters: Rams DL (three major IR), WR/CB/LB; Raiders DL.

Impact: Los Angeles has lost multiple important defensive linemen, significantly weakening its interior run defense and pass rush. Adams' absence also removes a major receiving weapon. The Raiders have an opportunity to attack the Rams' defensive front.

6. Packers vs. Lions — Green Bay DL/OL/EDGE, Detroit Secondary

Packers

  • DL: Javon Hargrave (Achilles, IR); Jonathan Ford (calf, IR); Warren Brinson (calf, IR); Jordon Riley (Achilles, PUP).

  • EDGE: Micah Parsons (ACL, PUP); Collin Oliver (Achilles, IR).

  • LB: Edgerrin Cooper (Achilles, IR).

  • OL: Zach Tom (knee, IR); Aaron Banks (knee/toe, LP).

  • WR: Jayden Reed (neck, IR); Matthew Golden (shoulder, LP); Christian Watson (ankle, LP).

  • CB: Benjamin St-Juste (hamstring, LP); Brandon Cisse (neck/shoulder, LP).

  • QB: Jordan Love (back, LP).

Lions

  • S: Brian Branch (Achilles, PUP/return candidate); Kerby Joseph (knee, PUP).

  • CB: Avonte Maddox (foot, IR); Rock Ya-Sin (hamstring, LP).

  • OL: Ben Bartch (foot, IR); Cade Mays (wrist, IR).

  • LB: Devin White (forearm, IR).

  • RB: Isiah Pacheco (back, IR).

Clusters: Packers DL/EDGE/OL; Lions secondary/OL.

Impact: Green Bay's defensive front remains significantly compromised by the losses of Hargrave, Parsons and Cooper, with multiple additional linemen unavailable. Detroit's biggest issue is the secondary, although Branch is progressing toward a possible return.

7. Chiefs vs. Seahawks — Kansas City OL/WR, Seattle RB/LB

Chiefs

  • WR: Rashee Rice (hamstring/knee, DNP); Tyquan Thornton (ankle, IR).

  • OL: Jaylon Moore (concussion, DNP); Josh Simmons (back, DNP).

  • TE: Travis Kelce (ankle, LP).

  • CB: L'Jarius Sneed (knee, LP).

  • DL: Omarr Norman-Lott (ACL, PUP).

  • QB: Patrick Mahomes (knee, FP).

Seahawks

  • RB: Zach Charbonnet (ACL, PUP); Jadarian Price (chest, IR).

  • OL: Anthony Bradford (knee, IR).

  • TE: Elijah Arroyo (shoulder, reported OUT).

  • LB: Drake Thomas (ankle, existing injury); Chazz Surratt (calf, existing injury).

Clusters: Chiefs OL/WR; Seahawks RB/LB.

Impact: Kansas City's tackle injuries create a protection concern, while Rice's absence limits receiving options. Seattle's backfield is depleted by Charbonnet and Price, increasing pressure on the remaining running backs.

8. Browns vs. Titans — Cleveland DL/OL Crisis

Browns

  • DL: Alex Wright (Achilles, IR); Kalia Davis (quad, IR); Mike Hall Jr. (ankle, DNP); Mason Graham (knee/ankle, LP); Maliek Collins (foot, LP); Derek Barnett (ankle, LP).

  • OL: Teven Jenkins (back, DNP); Elgton Jenkins (knee, DNP); Tytus Howard (knee, LP).

  • RB: Dylan Sampson (knee, IR); Quinshon Judkins (ankle, LP).

  • QB: Dillon Gabriel (back, listed IR by injury tracker).

  • LB: Jeremiah Owusu-Koramoah (neck, PUP); Carson Schwesinger (ankle, DNP).

  • S: Grant Delpit (concussion/shoulder, DNP).

Titans

  • S: Kevin Winston Jr. (quad, LP); Tony Adams (ankle, LP).

  • EDGE: Jaylen Harrell (ACL, IR); Tanoh Kpassagnon (IR).

  • WR: Calvin Ridley (hip, LP).

Clusters: Browns DL/OL/LB/RB; Titans secondary.

Impact: Cleveland is significantly more injured, especially along both lines. Tennessee's relative health could create an advantage in the trenches, particularly against the Browns' depleted defensive interior.

9. Dolphins vs. Jets — New York RB/Defensive Front

Dolphins

  • LB: Kyle Louis (knee, IR).

  • S: Ronnie Harrison Jr. (hamstring, IR).

  • EDGE: Trey Moore (ankle, IR); Robert Beal Jr. (hamstring, LP).

  • OL: Jonah Savaiinaea (ankle, FP).

  • CB: Reese Taylor (quad, DNP).

  • QB: Malik Willis (thumb, FP).

Jets

  • RB: Breece Hall (quad, DNP).

  • EDGE: Joseph Ossai (ankle, DNP); Will McDonald IV (toe, LP); Braiden McGregor (pectoral, IR).

  • DL: David Onyemata (groin, IR).

  • OL: Dylan Parham (knee, LP).

  • WR: Adonai Mitchell (finger, LP); Arian Smith (ACL, IR).

Clusters: Jets RB/EDGE/DL; Dolphins front seven.

Impact: Hall's availability is the biggest offensive variable. New York's pass rush is weakened by multiple injuries, which could provide Miami with better protection and more time to throw.

10. Buccaneers vs. Panthers — Carolina CB/OL/WR, Tampa WR/OL

Buccaneers

  • WR: Emeka Egbuka (concussion/foot, DNP); Jalen McMillan (PCL, IR).

  • OL: Luke Goedeke (calf, DNP).

  • S: Antoine Winfield Jr. (ribs, LP).

  • CB: Benjamin Morrison (quad, FP).

  • QB: Baker Mayfield (thumb, FP).

  • RB: Bucky Irving (illness, DNP).

Panthers

  • CB: Jaycee Horn (quad, IR); Mike Jackson (groin, IR).

  • OL: Ikem Ekwonu (knee, PUP); Brady Christensen (hamstring, IR); Monroe Freeling (knee, FP).

  • WR: Xavier Legette (knee, IR).

  • RB: Jonathon Brooks (abdomen, IR); AJ Dillon (ankle, FP).

  • EDGE: Jaelan Phillips (hamstring, DNP; expected OUT); Thomas Incoom (calf, DNP).

Clusters: Panthers CB/OL/EDGE; Buccaneers WR/OL.

Impact: Carolina's cornerback losses are particularly important against Tampa Bay's passing offense, although Egbuka is also dealing with an injury. Phillips' absence further reduces Carolina's ability to pressure Mayfield.

11. Colts vs. Vikings — Indianapolis WR/TE/CB, Minnesota OL/TE

Colts

  • WR: Alec Pierce (heel, IR); Ashton Dulin (hamstring, DNP); Anthony Gould (concussion, DNP).

  • TE: Tyler Warren (groin, DNP); Drew Ogletree (ankle, DNP).

  • CB: Sauce Gardner (calf, DNP).

  • LB: Jaylon Carlies (ribs, DNP).

  • EDGE: Arden Key (hamstring, IR).

  • OL: Matt Goncalves (ankle, DNP).

Vikings

  • OL: Donovan Jackson (meniscus, IR); Christian Darrisaw (concussion, returning to practice).

  • TE: Josh Oliver (biceps, IR); T.J. Hockenson (concussion, returning to practice).

  • RB: Jordan Mason (thumb, IR).

  • WR: Jordan Addison (hamstring, returning to practice).

  • S: Jamal Adams (quad, IR).

Clusters: Colts WR/TE/CB; Vikings OL/TE/RB.

Impact: Indianapolis has several major offensive injuries, with Pierce on IR and Warren missing Wednesday practice. Gardner's calf injury is particularly concerning against Minnesota's receiving corps. The Vikings have multiple potential returns, but their offensive-line depth remains weakened.

12. 49ers vs. Falcons — San Francisco WR/DL, Atlanta CB/Pass Rush

49ers

  • WR: Ricky Pearsall (PCL, IR); Christian Kirk (calf, IR); Demarcus Robinson (ankle, IR); Mike Evans (Achilles, DNP); Deebo Samuel (hamstring, DNP).

  • DL: Alfred Collins (knee, IR); Mikail Kamara (knee, IR); Sam Okuayinonu (foot, IR).

  • EDGE: Nick Bosa (calf, DNP).

  • CB: Nate Hobbs (groin, IR).

  • LB: Dre Greenlaw (suspension, return eligibility needs confirmation).

Falcons

  • CB: A.J. Terrell Jr. (groin, IR return window); C.J. Henderson (groin, LP); Avieon Terrell (hamstring, LP).

  • EDGE: Jalon Walker (ACL, IR); Samson Ebukam (hamstring, LP); Za'Darius Smith (neck, LP). James Pierce Suspension

  • LB: Divine Deablo (forearm, DNP).

  • OL: Cameron Williams (ankle, IR); Michael Jerrell (biceps, LP).

Clusters: 49ers WR/DL; Falcons CB/EDGE.

Impact: San Francisco's receiving corps is severely depleted, and its defensive-line absences are substantial. Atlanta's secondary injuries could provide an opportunity for the remaining 49ers receivers, but the Falcons' own pass-rush losses also matter.

13. Giants vs. Texans — New York QB/EDGE/CB, Houston WR/Secondary

Giants

  • QB: Jaxson Dart (meniscus, IR).

  • EDGE: Brian Burns (ACL, IR); Chauncey Golston (neck, IR).

  • DL: Roy Robertson-Harris (Achilles, IR).

  • CB: Paulson Adebo (knee, IR); Greg Newsome II (concussion, current injury); Colton Hood (concussion, current injury).

  • S: Tyler Nubin (neck, current injury).

  • WR: Darnell Mooney (neck, current injury); Calvin Austin III (knee, IR).

  • TE: Theo Johnson (neck, current injury).

  • OL: Jermaine Eluemunor (calf, current injury).

Texans

  • WR: Tank Dell (ACL/MCL, IR); Jayden Higgins (ACL, IR).

  • S: Jalen Pitre (shoulder/AC joint, current injury); Reed Blankenship (concussion, current injury).

  • RB: David Montgomery (groin, current injury).

  • LB: E.J. Speed (quad, PUP).

  • DL: Dylan Horton (Achilles, IR).

Clusters: Giants QB/EDGE/CB; Texans WR/secondary.

Impact: New York's quarterback and pass-rush losses are major, especially with Burns unavailable. Houston's receiving corps is weakened by the losses of Dell and Higgins, while Pitre and Blankenship create a potential secondary cluster.

14. Cowboys vs. Eagles — Philadelphia QB/OL/RB/TE Crisis

Cowboys

  • S: Jalen Thompson (hamstring, IR); P.J. Locke (foot, IR).

  • LB: Marist Liufau (forearm, IR); DeMarvion Overshown (hamstring, recent injury); Dee Winters (Achilles, recent injury).

  • OL: Matt Hennessy (neck, IR); Drew Shelton (hamstring, recent injury).

  • DL: Jonathan Bullard (calf, IR).

  • WR: KaVontae Turpin (ribs, recent injury).

Eagles

  • QB: Jalen Hurts (calf, IR).

  • OL: Landon Dickerson (knee, IR); Lane Johnson (personal, reported retired).

  • RB: Will Shipley (foot, IR); Tank Bigsby (abdomen, IR); Saquon Barkley (hamstring, recent injury).

  • TE: Grant Calcaterra (back, IR); Eli Stowers (quad, IR).

  • CB: Jakorian Bennett (knee, IR); Michael Carter II (abdomen, recent injury).

  • EDGE: Jalyx Hunt (ankle, recent injury).

  • DL: Jordan Davis (ankle, recent injury).

Clusters: Eagles QB/OL/RB/TE, Cowboys LB/secondary.

Impact: Philadelphia has one of the league's largest cumulative offensive injury burdens. Hurts, Dickerson and Shipley are on IR, while Barkley's hamstring and Lane Johnson's availability add further concerns. Dallas is healthier offensively but has notable linebacker and secondary losses.

Biggest NFL Week 7 Injury Clusters

  1. Patriots OL/CB: Four guards unavailable, three cornerbacks OUT.

  2. Eagles offense: Hurts, Dickerson, Shipley and multiple tight ends on IR.

  3. Cardinals: Major injuries across OL, RB and secondary.

  4. Rams DL: Ford, Turner and Garrett on IR; Adams also out at WR.

  5. Packers defensive front: Parsons, Hargrave, Cooper and multiple interior defenders unavailable.

  6. 49ers WR/DL: Multiple IR players at both positions.

  7. Browns trenches: Extensive OL and DL injuries.

  8. Panthers CB/OL: Horn and Jackson on IR, with Ekwonu and Christensen unavailable.

  9. Ravens QB/OL: Jackson limited; three centers on IR.

  10. Giants QB/pass rush: Dart, Burns and Golston on IR.

Bye teams: Bills, Jaguars, Chargers and Commanders.