NFL Week 10 brings another wave of significant injuries across the league, with several key players ruled out and others facing game-time decisions that could impact Sunday's matchups.

SICscore.com breaks down the latest NFL Week 10 injury updates, final player statuses and key developments affecting fantasy football and betting ahead of kickoff.

QUESTIONABLE

  • Travis Kelce, Chiefs (right ankle): Questionable to return against the Falcons after injuring his ankle on a 23-yard reception in the first quarter. Kelce was evaluated on the sideline before heading to the locker room for further testing.

  • Omar Cooper Jr., Jets (ankle): Questionable to return after his ankle was rolled up on from behind while blocking. Dr. David Chao (@ProFootballDoc) is concerned about a mild high ankle sprain. Cooper previously spent time on injured reserve with an ankle injury and entered Week 10 listed on the injury report with an ankle issue.

  • Brandon Cisse, Packers (ribs): Questionable to return to Sunday's Week 10 game against the Vikings after suffering a rib injury, according to the team.

Concussion Evaluations

  • Trey Smith, Chiefs (concussion evaluation): Headed to the locker room during Week 10 against the Falcons and is being evaluated for a concussion, according to the Chiefs. Mike Caliendo replaced Smith at right guard.

RULED OUT

  • Drake Maye, Patriots (ankle): Ruled out of Week 10 against the Lions after suffering an ankle injury on a first-quarter sack. Video raises concern for a high ankle sprain, though the Patriots have not confirmed a diagnosis. Dr. David Chao (@ProFootballDoc) expects Maye to miss additional time, potentially extending beyond New England's Week 11 bye.

  • Aidan Hutchinson, Lions (right knee): Suffered a right knee injury while celebrating a play in the first quarter against the Patriots in Munich. Dr. David Chao (@ProFootballDoc) believes Hutchinson tore his right ACL based on video analysis, though the Lions have not confirmed the diagnosis.

  • A.J. Brown, Patriots (hamstring): Suffered a hamstring injury during Sunday's Week 10 game against the Lions in Munich and was subsequently ruled out for the remainder of the game.

  • Bernhard Raimann, Colts (concussion): Ruled out for the remainder of Sunday's Week 10 game against the Dolphins after being evaluated for a concussion, according to the team.