Our Week 8 NFL injury report breaks down the biggest injuries for every matchup, including key starters, players on injured reserve (IR), practice participation, potential absences and injury clusters that could create advantages on the field. We highlight the most important injury news, how each team's overall health could affect performance and which matchups present the biggest injury-related betting angles heading into Week 8.
Top 8 Injury Matchups
Cardinals–Cowboys: Arizona's widespread OL, front-seven and secondary injuries.
Vikings–Lions: Detroit's injuries to St. Brown, Gibbs and multiple defensive linemen.
Eagles–Commanders: Philadelphia's QB/WR/RB crisis and Washington's receiving losses.
Chargers–Rams: Derwin James' setback, Chargers secondary and Rams receiving/TE injuries.
Panthers–Packers: Confirmed offensive-line absences on both sides.
Ravens–Bills: Lamar Jackson's return, Baltimore defensive concerns and Buffalo OL injuries.
Falcons–Buccaneers: Atlanta defensive-front/secondary injuries and Tampa Bay's offensive concerns.
Chiefs–Broncos: Rice's potential return, Waddle's chest injury and Denver's defensive availability.
Biggest Wednesday Injury Developments
Lamar Jackson: FP, trending toward a return.
Rashee Rice: LP, first practice since Week 4.
Amon-Ra St. Brown and Jahmyr Gibbs: Both DNP.
Saquon Barkley: DNP following back tightness Monday.
Derwin James: DNP, setback with possible IR consideration.
Jaylen Waddle: DNP after aggravating chest injury.
Emeka Egbuka: LP, attempting to return from concussion/foot injuries.
Aaron Jones: DNP following Week 7 knee injury.
Terry McLaurin: Confirmed OFS, now on IR.
1. Panthers vs. Packers — Carolina OL/EDGE vs. Green Bay OL/LB Crisis
Thursday Night Football — final game designations
Panthers
OL: Damien Lewis (knee, OUT); Torricelli Simpkins III (ankle, OUT).
EDGE: Jaelan Phillips (hamstring, OUT).
CB: Akayleb Evans (triceps/knee, OUT).
DL: Bobby Brown III (hand, Q).
QB: Bryce Young (FP, cleared).
Packers
OL: Sean Rhyan (ankle, OUT); Travis Glover (knee, OUT); Aaron Banks (LP).
LB: Zaire Franklin (shin, OUT).
DL: Devonte Wyatt (LP); Anthony Campbell (LP).
WR: Matthew Golden (DNP).
CB: Benjamin St-Juste (FP).
Injury clusters: Carolina OL (two OUT), EDGE and CB; Green Bay OL (two OUT), LB and defensive interior.
Injury impact: Both teams have significant offensive-line problems, making pass protection a central matchup concern. Carolina's loss of Phillips weakens its pass rush, while Green Bay is missing Franklin at linebacker.
2. Ravens vs. Bills — Lamar Jackson Return and Buffalo Offensive-Line Concerns
Ravens
- QB: Lamar Jackson (ankle, FP Wednesday). First full practice since the Week 4 injury after missing three games.
Bills
OL: Spencer Brown (back, DNP Wednesday).
DL: Ed Oliver (knee, returned to practice after missing two games).
Injury clusters: Baltimore QB recovery; Buffalo offensive tackle and defensive interior.
Injury impact: Jackson's full participation is a major positive for Baltimore and suggests he is moving closer to returning. Buffalo's right-tackle situation is important against the Ravens' pass rush, while Oliver's potential return would strengthen the Bills' defensive front.
3. Chiefs vs. Broncos — Rashee Rice Return Watch
Chiefs
- WR: Rashee Rice (hamstring/knee, LP Wednesday). First practice since Week 4; missed three consecutive games.
Broncos
- WR: Jaylen Waddle (chest, injury being monitored).
Injury clusters: Kansas City WR; Denver receiving corps.
Injury impact: Rice's return to practice could materially improve Kansas City's passing game, but his limited participation does not guarantee availability. His Thursday and Friday workload will be important in determining whether he returns against Denver.
4. Vikings vs. Lions — Detroit Offensive Skill-Position Injuries
Lions
WR: Amon-Ra St. Brown (ankle, DNP Wednesday). Injured during Week 7 against Green Bay.
RB: Jahmyr Gibbs (shoulder, DNP Wednesday).
Vikings
- No additional Wednesday starter injury status independently confirmed in the information reviewed so far.
Injury clusters: Detroit WR/RB, with two high-usage offensive playmakers affected.
Injury impact: Detroit's two most important offensive skill players missed Wednesday practice. Neither has been definitively ruled out, but simultaneous injuries to St. Brown and Gibbs would substantially affect the Lions' offensive ceiling if either is limited Sunday.
5. Cardinals vs. Cowboys — Arizona OL/Front Seven and Secondary
Cardinals
OL: Jon Gaines II (DNP), Isaac Seumalo (DNP), Elijah Wilkinson (DNP).
EDGE/LB: Josh Sweat (DNP), Zaven Collins (DNP), Mack Wilson (DNP).
DL: Walter Nolen (DNP).
S: Budda Baker (DNP), Andrew Wingard (LP).
CB: Max Melton (LP), Kei'Trel Clark (LP).
RB: Tyler Allgeier (DNP), Jeremiyah Love (ankle, LP).
QB: Carson Beck (back, LP).
Cowboys
LB: Dee Winters (DNP); Marist Liufau (FP).
DL: Quinnen Williams (LP).
S: Caleb Downs (LP); P.J. Locke (FP).
WR: George Pickens (LP); KaVontae Turpin (DNP).
OL: Drew Shelton (LP).
Injury clusters: Arizona OL (three DNP), front seven (four DNP) and secondary; Dallas LB and special-teams/WR depth.
Injury impact: Arizona has one of the league's largest Wednesday injury lists, with concerns across both trenches and its secondary. Dallas looks comparatively healthier, although Pickens' status and the availability of its linebackers are worth monitoring.
6. Falcons vs. Buccaneers — Atlanta Defensive Injuries vs. Tampa Bay Offensive Line
Falcons
CB: Billy Bowman Jr. (DNP); Avieon Terrell (LP).
EDGE: Za'Darius Smith (DNP); Samson Ebukam (LP).
LB: Divine Deablo (DNP).
RB: Brian Robinson (DNP).
OL: Jawaan Taylor (LP); Cameron Williams (FP).
Buccaneers
WR: Emeka Egbuka (concussion/foot, LP).
OL: Luke Goedeke (DNP).
EDGE: Yaya Diaby (LP).
RB: Kenny Gainwell (DNP).
S: Antoine Winfield Jr. (FP).
QB: Baker Mayfield (FP).
Injury clusters: Atlanta secondary, EDGE/LB and RB; Tampa Bay WR, OL and EDGE.
Injury impact: Atlanta has several important defensive contributors unavailable for Wednesday practice. Tampa Bay is trying to regain Egbuka after his Week 7 absence, but Goedeke remains a protection concern.
7. Colts vs. Jaguars — Indianapolis TE/CB and Linebacker Injuries
Colts
TE: Tyler Warren (groin, LP); Andrew Ogletree (LP).
CB: Sauce Gardner (calf, LP); Justin Walley (DNP).
LB: Bryce Boettcher (DNP); C.J. Allen (FP).
OL: Matt Goncalves (LP).
WR: Anthony Gould (LP).
Jaguars
S: Antonio Johnson (DNP).
CB: Montaric Brown (FP).
WR: Jakobi Meyers (LP).
DL: Ruke Orhorhoro (LP).
Injury clusters: Indianapolis TE, CB and LB; Jacksonville secondary.
Injury impact: Indianapolis could regain Warren and Gardner after both missed Week 7, but neither was a full participant Wednesday. Their availability will be particularly important against Jacksonville.
8. Chargers vs. Rams — Derwin James Setback and Rams TE/OL Injuries
Chargers
S: Derwin James (hamstring, DNP Wednesday). Coach Jim Harbaugh reported a rehabilitation setback and said IR is a possibility.
OL: Kayode Awosika (fibula, DNP).
CB: Deane Leonard (concussion, DNP).
WR: Ladd McConkey (concussion, FP); Brenen Thompson (quadriceps/hamstring, DNP).
EDGE: Khalil Mack (veteran rest, DNP; not necessarily injury-related).
Rams
WR: Davante Adams (hamstring, IR following surgery; estimated six-to-ten-week recovery).
TE: Colby Parkinson (ribs, DNP).
OL: Coleman Shelton (DNP).
CB: Trent McDuffie (groin, LP).
LB: Nate Landman (FP).
Injury clusters: Chargers safety, OL and CB; Rams WR, TE and OL.
Injury impact: Derwin James' setback is the biggest development. His absence could weaken the Chargers' secondary against the Rams' passing attack. Los Angeles' other team is dealing with offensive depth issues, but McDuffie's limited participation represents progress.
9. Patriots vs. Dolphins — New England Offensive Line vs. Miami Secondary
Patriots
WR: A.J. Brown (ankle/knee, LP).
OL: Ben Brown (knee, LP); Morgan Moses (foot, LP).
DL: DaQuan Jones (back, LP).
CB: Carlton Davis III, Channing Canada and Karon Prunty (all FP).
QB: Drake Maye (right shoulder, FP).
Dolphins
CB: Julius Brents (neck/concussion, DNP); Reese Taylor (quadriceps, LP).
OL: Kadyn Proctor (concussion, DNP).
S: Michael Taaffe (neck/foot, LP); Dante Trader Jr. (shoulder, LP).
TE: Greg Dulcich (ankle, LP).
WR: Malik Washington (knee, LP).
QB: Malik Willis (groin, FP).
Injury clusters: Patriots OL; Dolphins CB/safety and OL.
Injury impact: New England's secondary is significantly healthier after multiple players returned to full practice. Miami has several injured defensive backs, potentially creating opportunities for Maye and the Patriots' passing attack.
10. Browns vs. Steelers — Injuries Along Both Lines and Pittsburgh Secondary
Browns
OL: Tytus Howard (DNP); Elgton Jenkins (DNP).
EDGE: Jared Verse (DNP).
DL: Mason Graham (LP); Mike Hall Jr. (LP).
S: Grant Delpit (LP).
LB: Carson Schwesinger (LP).
RB: Dylan Sampson (LP).
Steelers
EDGE: T.J. Watt (DNP); Alex Highsmith (LP).
DL: Cameron Heyward (DNP).
CB: Jalen Ramsey (DNP); Brandin Echols (DNP); Doneiko Slaughter (DNP).
TE: Darnell Washington (DNP).
WR: Ben Skowronek (LP).
Injury clusters: Cleveland OL and DL/EDGE; Pittsburgh CB (three DNP) and defensive front.
Injury impact: Both teams have significant trench concerns, while Pittsburgh's cornerback group is particularly important to monitor. Wednesday absences do not necessarily indicate players will miss Sunday, especially for veterans such as Watt and Heyward.
11. Titans vs. Bengals — Tennessee Skill-Position Injuries
Titans
WR: Calvin Ridley (hip, LP); Carnell Tate (DNP).
RB: Tyjae Spears (DNP).
EDGE: John Franklin-Myers (DNP).
LB: Dorian Mausi (FP).
Bengals
WR: Ja'Marr Chase (ankle/rest, DNP).
DL: Jonathan Allen (DNP).
S: Kyle Dugger (DNP); Jordan Battle (LP).
Injury clusters: Tennessee WR/RB and EDGE; Cincinnati safety and defensive interior.
Injury impact: Tennessee's passing game remains a concern, with Ridley limited and Tate absent Wednesday. Chase's absence appears to be maintenance-related rather than a major new injury, but Thursday participation will help clarify that assessment.
12. Raiders vs. Jets — New York Defensive Front and Running Back Injuries
Raiders
TE: Brock Bowers (LP); Ian Thomas (LP).
EDGE: Patrick Johnson (DNP); Kwity Paye (LP).
DL: Folorunso Fatukasi (LP).
OL: DJ Glaze (LP).
LB: Quay Walker (LP).
Jets
RB: Breece Hall (quadriceps, LP); Braelon Allen (LP).
DL: Harrison Phillips (DNP); T'Vondre Sweat (DNP).
EDGE: David Bailey (DNP); Joseph Ossai (DNP).
LB: Demario Davis (DNP).
OL: Max Mitchell (DNP); Dylan Parham (LP).
Injury clusters: Jets defensive front (five DNP), RB and OL; Raiders TE and EDGE.
Injury impact: New York's defensive front is the biggest concern in this matchup, with multiple linemen and linebackers missing Wednesday. Hall's limited participation is encouraging following his quadriceps injury, but his availability and potential workload remain important.
13. Eagles vs. Commanders — Philadelphia QB/WR/RB Crisis and Washington Receiver Injuries
Eagles
QB: Jalen Hurts (calf/blood-clot issue, long-term absence; NFL reports indicate he is likely to miss the remainder of 2026). Tanner McKee is the replacement.
WR: DeVonta Smith (hamstring, missed Week 7); Dontayvion Wicks (ankle, missed Week 7).
RB: Saquon Barkley (hamstring/back, DNP Wednesday walkthrough). Played only nine snaps Monday against Dallas due to back tightness.
RB: Dameon Pierce (undisclosed injury, newly placed on IR); Will Shipley and Tank Bigsby (previously reported IR).
EDGE: Nolan Smith (concussion, missed Week 7).
Commanders
WR: Terry McLaurin (torn patellar tendon, IR/OFS).
WR: Stefon Diggs (DNP Wednesday); Treylon Burks (LP).
TE: John Bates (DNP).
DL: Javon Kinlaw (DNP); Jer'Zhan Newton (LP); Charles Omenihu (LP).
QB: Jayden Daniels (FP).
Injury clusters: Eagles QB, WR and RB; Washington WR and defensive interior.
Injury impact: Philadelphia continues to have major offensive personnel problems. Hurts' absence, uncertainty around Smith and Wicks, and Barkley's back injury leave the Eagles significantly compromised. Washington has its own receiver issues, particularly McLaurin's season-ending injury. Daniels' full participation is an important positive for the Commanders.
14. Bears vs. Seahawks — Monday Night Football
Monday, November 2 — initial official practice reports pending
Bears
LB: T.J. Edwards (hamstring, injury to monitor following Week 7); Jack Sanborn (concussion, missed Week 7).
EDGE: Dayo Odeyingbo (quadriceps, previously reported IR).
RB: Kyle Monangai (thumb/toe, missed Week 7).
OL: Jonah Jackson (previously returned to full practice).
Seahawks
RB: Zach Charbonnet (knee, missed Week 7); Jadarian Price (chest, previously reported IR).
LB: Drake Thomas (ankle, missed Week 7); Chazz Surratt (calf, missed Week 7).
EDGE: DeMarcus Lawrence (knee, questionable entering Week 7); Uchenna Nwosu (hip, questionable entering Week 7).
S: Nick Emmanwori (hip, questionable entering Week 7).
Injury clusters: Chicago LB and RB; Seattle RB, LB and EDGE.
Injury impact: Seattle's front-seven availability and running back depth are the main situations to monitor. Chicago's linebacker injuries remain relevant, but the Week 8 practice report is needed before drawing a firm conclusion about either team's health advantage.
