Patrick Mahomes (Kansas City Chiefs)
Injury: Torn ACL + Torn LCL (Left Knee)

Mahomes suffered a devastating knee injury in Week 15 against the Chargers after planting awkwardly during a scramble. The injury resulted in a torn ACL and torn LCL, requiring reconstructive surgery.

While Mahomes remains one of the NFL's elite quarterbacks, his mobility will be closely monitored throughout the offseason and training camp, and his availability for Week 1 remains uncertain. To provide insurance at the position, Kansas City brought in Justin Fields, who could be called upon if Mahomes is unable to suit up for the early portion of the season. The Chiefs remain committed to Mahomes as their franchise quarterback, but the addition of Fields gives them a capable contingency plan should his recovery timeline extend into the regular season.

Jayden Daniels (Washington Commanders)
Injury: Dislocated Left Elbow

Daniels suffered a dislocated elbow in Week 9 against Seattle after landing awkwardly during a blowout loss. Fortunately, no ligament damage was discovered and surgery was not required.

Washington shut him down for the remainder of the season, but he is expected to enter the 2026 campaign fully healthy.

Michael Penix Jr. (Atlanta Falcons)
Injury: Partially Torn ACL (Right Knee)

Penix suffered a partially torn ACL in Week 11 against Carolina and underwent season-ending surgery.

Atlanta turned back to Kirk Cousins following the injury, but Cousins has since moved on from the organization. In his place, the Falcons added Tua Tagovailoa, creating additional competition under center. Penix's recovery progress will be critical as he works his way back from knee surgery and attempts to establish himself in a quarterback room that now features another proven starter. His path to reclaiming the starting role is no longer guaranteed, making Atlanta's quarterback situation one of the most intriguing storylines entering the 2026 season.

Kyler Murray (Arizona Cardinals)
Injury: Midfoot Sprain

Murray was limited to just five appearances due to a lingering midfoot injury.

After arriving in Minnesota, Murray is expected to compete with J.J. McCarthy for the starting quarterback job. McCarthy has also dealt with injury concerns early in his career, creating one of the more intriguing quarterback battles heading into the 2026 season. Murray's experience and dual-threat ability provide significant upside if he can return to full health and secure the starting role.

Daniel Jones (Indianapolis Colts)
Injury: Torn Achilles

Jones suffered a torn Achilles in Week 14 against Jacksonville while attempting a pass in the first quarter.

The injury immediately ended his first season as Indianapolis' starter. Achilles injuries remain among the most difficult recoveries for quarterbacks, creating uncertainty surrounding his availability for Week 1 of the 2026 season but we at sicscore.com lean towards him starting.

Anthony Richardson (Indianapolis Colts)
Injury: Fractured Orbital Bone + Eye Injury

Richardson suffered a freak pregame warmup injury involving a resistance band on October 11.

The injury limited him to just five snaps all season and leaves major questions regarding both his health and long-term future with the Colts organization.

Will Levis (Tennessee Titans)
Injury: Season-Ending Shoulder Surgery

Levis underwent shoulder surgery before training camp and never appeared during the regular season.

Tennessee handed the offense to No. 1 overall pick Cam Ward last season, leaving Levis facing an uncertain future entering the 2026 campaign.

Deshaun Watson (Cleveland Browns)
Injury: Torn Achilles (Second Surgery)

Watson originally suffered an Achilles rupture in October 2024 before suffering a setback that required a second surgery in January 2025.

After missing the entire 2025 season, Watson enters 2026 as one of the league's biggest injury question marks due to both health concerns and uncertainty regarding his long-term effectiveness.

Sign up to our FREE Weekly Newsletter here for all of our best injury-insights, free injury-based picks and special discount offers!

WANT TO KNOW WHO TO PICK ON THE WNBA? - USE SIC PICKS FOR A GUARANTEED WINNING WNBA SEASON!
Look out for the WNBA Season SIC Picks pass for $99 - less than $1 a day

Expert WNBA Picks | WNBA Season Pass - BUY NOW

SIC PICKS ARE BASED ON INSIDER INJURY KNOWLEDGE FROM FORMER PRO SPORTS TEAM DOCTORS TO GIVE YOU A WINNING EDGE IN SPORTS BETTING!

SIC PICKS are powered by the proven SIC Score algorithms from our exclusive panel of former Pro Sports Team doctors to give you a sports betting edge. Each day our team of doctors analyze the players and teams and share their expert insights to help you make informed bets on the biggest unknown to sportsbooks and sports bettors - player health and injuries!  

For our Best Bets including spreads, totals, props and live in game with instant alerts as game day opportunities arise with research notes, sign up to SIC Picks here for less than $2 a day on an annual plan.

Sign up to SIC Picks today to get our picks sent direct to your cell!