These players have been shifted over the last week to the reserve/PUP or reserve/NFI list, meaning they will miss at least the first four games of the regular season.
Arizona Cardinals
NFI: CB, Antonio Hamilton (cooking incident)
Atlanta Falcons
None
Baltimore Ravens
OLB, Tyus Bowser (Achilles)
Bowser suffered an Achilles tear last January and is still working his way back. He has a chance to play Week 1, but will be limited early in the season.
RB, Gus Edwards (ACL)
The fifth-year back suffered his ACL tear in early September. His tear was contained just to the ACL, giving him a slightly more favorable timeline.
RB, J.K. Dobbins (ACL), undecided
Dobbins' left knee injury also included LCL damage, which makes his return more difficult. Baltimore will likely be cautious with the 23 year old. He was activated from PUP on Aug. 8, but is still not guaranteed to be ready for Week 1.
Buffalo Bills
CB, Tre'Davious White (ACL)
The All-Pro cornerback suffered a torn ACL last November and the Pro Football Docs said he may stay on the PUP list when the season officially starts. White has an SIC score of 41 for the Super Bowl hopeful Bills.
OG, Ike Boettger (Achilles)
Carolina Panthers
None
Chicago Bears
DE, Sam Kamara (undisclosed)
Cincinnati Bengals
LB, Joe Bachie (ACL)
S, Brandon Wilson (ACL)
Dallas Cowboys
None
Denver Broncos
OG, Tom Compton (back)
Detroit Lions
NFI list: WR, Jameson Williams (ACL)
The Docs believe Williams will likely stay on the NFI list to start the season – NFL Network's Tom Pelissero reported the Lions believe so as well – and he will be unavailable or ineffective until the second half of the season while he recovers from a January torn ACL.
DE, Romeo Okwara (Achilles)
DE, Josh Paschal (sports hernia)
CB, Jerry Jacobs (knee)
LB, Natrez Patrick (undisclosed)
Green Bay Packers
RB, Kylin Hill (ACL)
Houston Texans
NFI list: WR, John Metchie III (cancer)
Indianapolis Colts
None
Jacksonville Jaguars
None
Kansas City Chiefs
OT, Lucas Niang (torn patellar tendon)
Las Vegas Raiders
None
Los Angeles Chargers
None
Los Angeles Rams
NFI: LB, Travin Howard (groin)
Howard injured his groin training on his own in the offseason and will undergo surgery to fix the issue.
S, Quentin Lake (undisclosed)
Miami Dolphins
CB, Byron Jones (ankle)
Minnesota Vikings
LB, Ryan Connelly (knee)
WR, Blake Proehl (ACL)
New England Patriots
NFI: OG Andrew Stueber (torn hamstring)
New Orleans Saints
TE, Dylan Soehner (undisclosed)
New York Giants
C, Nick Gates (lower leg)
OT, Matt Peart (knee)
New York Jets
None
Philadelphia Eagles
TE, Tyree Jackson (ACL)
OL, Brett Toth (ACL)
Pittsburgh Steelers
None
San Francisco 49ers
CB, Jason Verrett (ACL)
NFI: DT, Kalia Davis (ACL)
Seattle Seahawks
CB, Tre Brown (patellar tendon)
LB, Jon Rhattigan (knee)
LB, Ben Burr-Kirven (ACL)
Tennessee Titans
LB, Monty Rice (Achilles)
K, Caleb Shudak (leg)
Washington Commanders
DE Chase Young (ACL)
The 2020 No. 1 overall pick suffered a torn right ACL and MCL last November. He has a SIC score of 68 for the 2022 season and will likely be eased back in and primarily used on the left side once he makes it back to the field.
C, Tyler Larsen (Achilles)
NFI: RB, Brian Robinson (lower leg gunshot wounds)