NFL Week 10 brings another round of significant injury concerns across the league, with several key players facing uncertain availability and others already expected to miss time.

SICscore.com is tracking the latest NFL Week 10 injury news, practice participation, game-day designations and potential return timelines. This report will be updated throughout the week as teams release new information and final injury reports.

Wednesday, November 11th

DNP

Kyler Murray, Vikings - Hamstring

Murray is projected as a nonparticipant on Wednesday's injury report as he continues recovering from a hamstring injury. Vikings head coach Kevin O'Connell said Murray began his running progression Wednesday, marking a step in his rehabilitation. Minnesota did not hold practice, so the injury designation is an estimate.

Bhayshul Tuten, Jaguars - Ankle/Foot

Tuten did not practice Wednesday as he deals with ankle and foot injuries ahead of Sunday's Week 10 matchup against the Titans. The Jaguars running back's availability will depend on his recovery throughout the practice week.

Jakobi Meyers, Jaguars - Ankle

Meyers did not practice Wednesday due to an ankle injury ahead of Sunday's Week 10 game against the Titans. The Jaguars wide receiver will have two more opportunities to practice before the team releases its final injury report.

Mike Evans, 49ers - Achilles

Evans will not practice Wednesday as he continues recovering from an Achilles injury that has sidelined him since before San Francisco's Week 8 bye. The 49ers wide receiver remains week-to-week, according to head coach Kyle Shanahan.

David Montgomery, Texans - Groin

Montgomery did not practice Wednesday as he continues recovering from a groin injury that sidelined him for Sunday's Week 9 game against the Chargers. The Texans running back is at risk of missing another game in Week 10, with Woody Marks handling the bulk of the backfield work in his absence.

Tyjae Spears, Titans - Knee

Spears did not practice Wednesday as he continues dealing with a lingering knee injury that has sidelined him since Week 7. The Titans running back missed Weeks 7 and 8, and the team's recent bye week has not provided enough recovery time for him to resume practicing ahead of Week 10.

Rhamondre Stevenson, Patriots - Plantaris Tendon Injury

Stevenson did not practice Wednesday as he continues recovering from a plantaris tendon injury suffered during Sunday's Week 9 loss to the Packers. The Patriots running back is expected to miss multiple weeks, with rest and rehabilitation planned rather than surgery. Stevenson is unlikely to play Sunday against the Lions, and New England's Week 11 bye will provide additional recovery time.

LIMITED

Garrett Wilson, Jets - Concussion

Wilson was limited in Wednesday's practice as he continues progressing through the NFL's concussion protocol. The Jets wide receiver missed Sunday's Week 9 game against the Chiefs due to the injury, but his return to practice is an encouraging sign ahead of Sunday's Week 10 matchup against the Bills. Wilson must clear concussion protocol before being eligible to play.

George Pickens, Cowboys - Hamstring

Pickens was limited in Wednesday's practice as he continues recovering from a hamstring injury that sidelined him for Sunday's Week 9 game against the Colts. The Cowboys wide receiver was limited throughout last week's practices before ultimately being held out. His return to practice is an encouraging sign ahead of Sunday's Week 10 matchup against the 49ers.

Drew Lock, Seahawks - Right Elbow/Oblique

Lock was limited in Wednesday's practice as he continues managing injuries to his throwing elbow and oblique. The Seahawks quarterback suffered the oblique injury during Sunday's Week 9 victory over the Cardinals, but subsequent testing showed encouraging results. Head coach Mike Macdonald previously expressed confidence that Lock would start Sunday's Week 10 game against the Raiders, with Sam Darnold ruled out due to a quadriceps injury.

Jared Goff, Lions - Chest

Goff was limited in Wednesday's practice due to a chest injury following Sunday's Week 9 victory over the Dolphins. The Lions quarterback struggled in the win, although it is unclear whether the injury affected his performance.

Amon-Ra St. Brown, Lions - Ribs

St. Brown was limited in Wednesday's practice as he continues managing a rib injury. The Lions wide receiver played through the issue during Sunday's Week 9 game against the Dolphins, finishing with eight receptions for 86 yards. He remains on the injury report ahead of Sunday's Week 10 matchup against the Patriots in Germany.

A.J. Brown, Patriots - Knee/Ankle

Brown was limited in Wednesday's practice after traveling with the Patriots to Germany ahead of Sunday's Week 10 matchup against the Lions. The wide receiver missed Week 9 against the Packers while managing knee and ankle injuries, but his return to practice gives him a chance to play this week.

Travis Etienne, Saints - Hamstring

Etienne was limited in Wednesday's practice after the Saints opened his 21-day practice window as he works toward returning from a hamstring injury. The running back can practice while remaining on injured reserve, but New Orleans must activate him to the 53-man roster before he can return to game action.

Deebo Samuel, 49ers - Hamstring

Samuel is expected to be limited in Wednesday's practice as he continues recovering from a hamstring injury that has sidelined him since October 11. The 49ers wide receiver missed Sunday's Week 9 victory over the Raiders and is working toward a return in Week 10.

Hunter Henry, Patriots - Foot

Henry was limited in Wednesday's practice as he continues to manage a foot injury. The Patriots tight end played through the issue in Sunday's Week 9 loss to the Packers despite being limited in practice throughout last week. He finished with three receptions for 35 yards.

Harold Fannin, Browns - Groin

Fannin was limited in Wednesday's practice as he continues managing a recurring groin injury. The Browns tight end played through the issue during Sunday's Week 9 game against the Saints, finishing with two receptions for 42 yards and a touchdown, all in overtime.

Bam Knight, Cardinals - Concussion

Knight returned to practice Wednesday after missing Sunday's Week 9 game against the Seahawks due to a concussion. The Cardinals running back was seen wearing a yellow non-contact jersey. His return to practice is an encouraging step toward potentially playing in Sunday's Week 10 matchup against the Rams. He was limited.

FULL

Patrick Mahomes, Chiefs - Right Elbow

Mahomes is expected to practice in full Wednesday ahead of Sunday's Week 10 matchup against the Falcons, according to Chiefs head coach Andy Reid. The quarterback suffered a right elbow injury during Sunday's Week 9 victory over the Jets, but an MRI revealed no major structural damage. Mahomes told reporters the injury is now a matter of pain management and is expected to play Sunday.

MarShawn Lloyd, Packers - Knee

Lloyd was not listed on Wednesday's injury report after missing Sunday's Week 9 game against the Patriots with a knee injury. The Packers running back appears to have recovered from the issue and is on track to return for Sunday's Week 10 matchup against the Vikings.

OUT/IR

Josh Jacobs, Packers - Fractured Ring Finger (OUT Week 10)

Jacobs is expected to undergo surgery later this week to repair a fractured ring finger suffered during Sunday's Week 9 game against the Patriots. The Packers running back has been ruled out for Sunday's Week 10 matchup against the Vikings but could return within two to three weeks, according to reports. Green Bay will decide Saturday whether to place Jacobs on injured reserve, although an IR designation is not guaranteed. The Packers have a Week 11 bye, potentially giving Jacobs an opportunity to return in Week 12.

Malik Willis, Dolphins - Groin (Injured Reserve)

The Dolphins placed Willis on injured reserve Tuesday due to a groin injury, sidelining their starting quarterback for at least four games. Willis had received treatment for the injury over the past two weeks but had not missed practice or game action before Miami's decision to place him on IR.

TreVeyon Henderson, Patriots - Illness

Henderson has been ruled out for Sunday's Week 10 game against the Lions in Germany as he continues dealing with an undisclosed medical issue. The Patriots running back also missed Week 9 against the Packers after being hospitalized for unexplained neurological symptoms. His return timeline remains unknown, leaving Corey Kiner in line for an expanded workload with Rhamondre Stevenson also expected to miss Sunday's game.